N.S., not significant
RNA and protein analyses showed that NRF2 silencing by sh NRF2 significantly decreased (Fig
These shifts can make it easier to slip back into old habits and harder to maintain weight loss
This helps preserve lean muscle mass, promoting a healthier body composition, which is vital for long-term fitness and overall wellness
We also observed upregulation of mesenchymal markers ( VIM and TWIST ) and downregulation of epithelial markers ( CDH1 , CLDN7 and TJP3 , Figures 2F, G ) , consistent with earlier observations in other persister cell models ( Figure 2 CRC Persister Cells Are Vulnerable to Ferroptosis To effectively eliminate CRC DTP cells, we sought to identify therapeutic vulnerabilities in persister cells that are absent in parental and regrown cells
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